PERFORMING THE THERMOFLUOR ASSAY WITH AND WITHOUT BOUND DRUGS
Performing and interpreting biophysical analyses of a protein with and without bound drugs using the Thermofluor assay involves several steps. The Thermofluor assay, also known as thermal shift assay or differential scanning fluorimetry, is a powerful tool for studying protein…
DRUGS COMMONLY USED IN THE TREATMENT OF TYPHOID FEVER
Typhoid fever is a bacterial infection caused by the bacterium Salmonella enterica serotype Typhi. It is primarily transmitted through contaminated food and water, and it affects millions of people worldwide, particularly in developing countries with poor sanitation. The treatment of…
MODE OF ACTION OF ANDROGEN HORMONES AND ANTI-ANDROGEN DRUGS
Androgen hormones are a class of steroid hormones that play a crucial role in the development and maintenance of male characteristics. The primary androgen hormone is testosterone, which is produced primarily in the testes in males and in smaller amounts…
HEART FAILURE TREATMENT DRUGS
Introduction There are several classes of drugs used in the treatment of heart failure. These include: Angiotensin-Converting Enzyme (ACE) Inhibitors: Examples include Lisinopril and Enalapril. They help relax blood vessels and reduce the workload on the heart. Angiotensin II Receptor…
ANTIDIARRHEAL DRUGS AND LAXATIVE AGENTS
Introduction Antidiarrheal drugs are used to treat diarrhea by slowing down bowel movements and reducing fluid secretion. Common examples include loperamide and bismuth subsalicylate. Laxative agents, on the other hand, help relieve constipation by promoting bowel movements. They can be…
DRUGS OF ABUSE PHARMACOLOGY
Introduction Drugs of abuse refer to substances that have the potential to be misused or cause addiction and harmful effects on the individual’s physical and mental health. These drugs can alter the brain’s chemistry, leading to various behavioral, psychological, and…
DRUGS USED IN PEPTIC ULCER DISEASE
GI Ulceration & Drugs: Prevention Several drugs or drug groups are associated with gastrointestinal (GI) ulceration. Here are some major ones: Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs, such as ibuprofen, naproxen, and aspirin, are commonly used for pain relief and reducing…
DRUGS ACTING ON THE BLOOD INFLAMMATION AND GOUT
Introduction Drugs acting on the blood, inflammation, and gout encompass a wide range of medications used to treat various conditions related to the circulatory system, inflammatory responses, and gout attacks. Here’s an overview of some commonly used drugs in each…
A REVIEW OF DRUGS ACTING ON THE RESPIRATORY SYSTEM
Allergy Meds Overview Bronchodilators: Short-acting beta-agonists (SABAs): Examples include albuterol and levalbuterol. They act quickly to relax the smooth muscles in the airways, providing immediate relief from bronchoconstriction during asthma attacks or acute exacerbations. They are often used as rescue…
A CLOSER LOOK AT CARDIOVASCULAR AND RENAL DRUGS
Cardiovascular and renal disorders Cardiovascular and renal disorders encompass a wide range of conditions affecting the heart, blood vessels, and kidneys. These disorders can have significant implications for overall health and require appropriate medical management. Here are descriptions of some…
THE IMPACT OF DRUGS ACTING ON THE AUTONOMIC NERVOUS SYSTEM
Autonomic Nervous System Overview The autonomic nervous system (ANS) is a division of the peripheral nervous system that controls and regulates involuntary bodily functions, maintaining homeostasis and responding to internal and external stimuli. It acts largely unconsciously and automatically, regulating…
A GENERAL REVIEW OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of medications commonly used to reduce inflammation, relieve pain, and lower fever. They work by inhibiting the production of prostaglandins, which are chemical messengers that play a role in inflammation, pain, and fever.…
A COMPREHENSIVE OVERVIEW OF ANTINEOPLASTIC DRUGS
Introduction Antineoplastic drugs, also known as anticancer or chemotherapy drugs, are a class of medications used in the treatment of cancer. They are designed to inhibit or destroy cancer cells, preventing their growth, proliferation, and spread within the body. These…
EXPLORING THE BENEFITS OF ANTIPROTOZOAL AND ANTHELMINTIC DRUGS
Malaria Treatment Options Malaria is a life-threatening disease caused by the Plasmodium parasite and transmitted through the bite of infected mosquitoes. The treatment of malaria involves the use of various therapeutic options, each with its own mechanisms of action, indications,…
DRUGS USED IN SCHIZOPHRENIA AND OTHER PSYCHOTIC DISORDERS
Introduction There are several types of drugs commonly used in the treatment of schizophrenia and other psychotic disorders. These medications are primarily aimed at reducing the symptoms of psychosis, such as hallucinations, delusions, and disorganized thinking. The specific medication prescribed…
EXPLORING THE MECHANISMS OF ACTION OF VASODILATOR DRUGS
Peripheral Vasodilators for Hypertension Peripheral vasodilators are a class of drugs used in the treatment of hypertension (high blood pressure). They work by relaxing the smooth muscles in the walls of the blood vessels, which leads to the widening (dilation)…
THE ULTIMATE REVELATION OF ANTIHYPERTENSIVE DRUGS
Hypertension Drug Groups There are several groups of drugs that are commonly used to treat hypertension, also known as high blood pressure. Here are the major groups of drugs used in the treatment of hypertension and an example of each:…
THE IMPACT OF DRUGS ON ANEMIA TREATMENT
Introduction Anemia is a medical condition characterized by a reduced number of red blood cells or a decrease in the amount of hemoglobin in the blood, which can cause fatigue, weakness, and other symptoms. The treatment of anemia depends on…
DRUGS AND DRUG ABUSE
Nigeria is a society in which the use of mind-altering substances is fast becoming a central part of the culture. On television, you are certain to see advertisement with successful, attractive people drinking beer, smoking cigarettes, swallowing malaria or pain-relieving…