IN DIABETIC PATIENTS WHO ARE IN PREMATURE LABOR, THE DRUG OF CHOICE IS

• A. A beta-sympathomimetic
• B. Magnesium sulfate ✓
• C. Prostaglandin synthetase inhibitors
• D. Salbutamol

In diabetic patients who are in premature labor, the drug of choice is magnesium sulfate. Magnesium sulfate is commonly used as a tocolytic agent to delay preterm labor and prevent premature birth in diabetic patients due to its effectiveness in relaxing uterine smooth muscle and reducing contractions.

Magnesium sulfate works by blocking neuromuscular transmission and decreasing acetylcholine release at the myoneural junction, leading to smooth muscle relaxation. This mechanism of action helps to inhibit uterine contractions and delay labor progression, providing crucial time for administering corticosteroids for fetal lung maturation or transferring the mother to a facility with appropriate neonatal care.

Additionally, magnesium sulfate has been shown to have neuroprotective effects on the developing fetal brain, making it a favorable choice for use in diabetic pregnant women who are at higher risk of preterm delivery and associated complications.

Overall, magnesium sulfate is considered the drug of choice for tocolysis in diabetic patients experiencing premature labor due to its efficacy in delaying labor, reducing neonatal morbidity and mortality, and providing neuroprotection to the developing fetus.