MEDICAL
PROOPIOMELANOCORTIN IS SYNTHESIZED AND RELEASED FROM
A. Zona glomerulosa cells B. Gonadotropes C. Thyrotropes D. Pulmonary neuroendocrine bodies ✓ E. Erythrocytes Pulmonary neuroendocrine bodies, also known as Kulchitsky cells, are specialized neuroendocrine cells found in the lungs. These cells are responsible for the synthesis and…
THE MAJOR SOURCE OF ESTROGENS IN THE HUMAN FETUS IS
A. The fetal ovary B. The fetal testis C. The fetal zone of the fetal adrenal cortex D. The definitive zone of the fetal adrenal cortex E. The placenta ✓ The major source of estrogens in the human fetus…
ANTENATAL STEROID THERAPY RESULTS IN A REDUCTION IN WHICH OF THESE MAJOR COMPLICATIONS OF PREMATURITY
A. Intraventricular hemorrhage (IVH) and necrotizing enterocolitis (NEC) ✓ B. IVH and jaundice C. IVH and pneumonia D. IVH and gastroinestinal reflux Antenatal steroid therapy results in a reduction in the major complications of prematurity, specifically option A: Intraventricular…
THE LUNG CELLS RESPONSIBLE FOR SURFACTANT SYNTHESIS ARE
A. Type 1 pneumocytes B. Bronchial epithelium C. Type 2 pneumocytes ✓ D. Endothelial cells The lung cells responsible for surfactant synthesis are Type 2 pneumocytes. Type 2 pneumocytes, also known as septal cells or type II alveolar cells,…
CONTRAINDICATIONS TO TOCOLYSIS WITH MAGNESIUM SULFATE INCLUDE
A. Oligohydramnios B. Myasthenia gravis ✓ C. Thyroid disease D. Uncontrolled diabetes Tocolysis is the process of inhibiting uterine contractions in order to delay preterm labor. Magnesium sulfate is a commonly used medication for tocolysis. However, there are certain…
WHICH OF THE FOLLOWING HEMOGLOBINOPATHIES DOES NOT CAUSE SICKLE-CELL CRISIS
A. Hemoglobin SA ✓ B. Hemoglobin SS C. Hemoglobin SC D. Hemoglobin S/β-thalassemia Hemoglobinopathies are a group of genetic disorders characterized by abnormalities in the structure or production of hemoglobin, the protein responsible for carrying oxygen in red blood…
WHICH OF THE FOLLOWING ARE CONTRAINDICATIONS FOR BREASTFEEDING TERM, HEALTHY INFANTS
A. Maternal hepatitis C B. Maternal hepatitis B C. Infant cleft lip or palate D. Infant galactosemia ✓ Contraindications for breastfeeding term, healthy infants include certain medical conditions that may pose risks to the infant or the mother. One…
THE META-ANALYSIS OF TRIALS COMPARING FORCEPS WITH VACUUMS CONCLUDED THAT
A. Forceps caused more neonatal trauma than vacuums B. Vacuums caused more perineal trauma than forceps C. Vacuums caused less perineal trauma than forceps ✓ D. Intracranial bleeding was only seen with vacuums In the meta-analysis of trials comparing…
THE TREATMENT OF A PROTRACTED ACTIVE PHASE IN THE PRESENCE OF CHORIOAMNIONITIS SHOULD INCLUDE
A. Oxytocin infusion ✓ B. Prompt Cesarean delivery C. Manual rotation of a malposition D. Amnioinfusion with antibiotics Chorioamnionitis is an infection of the fetal membranes (chorion and amnion) and amniotic fluid, typically caused by ascending bacteria from the…
INFANTS BORN TO A DIABETIC MOTHER ARE AT RISK OF
A. Hypoglycemia ✓ B. Hypoparathyroidism C. Hyperparathyroidism D. Hypothyroidism E. Hyperthyroidism Infants born to a diabetic mother are at risk of Hypoglycemia. This is because when a pregnant woman has diabetes, her high blood sugar levels can pass through…
IN CASES OF UNCERTAINTY (EQUIVOCAL NITRAZINE, FERNING, AND POOLING), WHICH OF THE FOLLOWING DYES SHOULD NOT BE INJECTED TRANSABDOMINALLY FOR THE DIAGNOSIS OF PRETERM PROM
A. Indigo carmine B. Methylene blue ✓ C. Evans blue D. Fluorescein In cases of uncertainty regarding the diagnosis of preterm premature rupture of membranes (PROM), it is important to exercise caution when considering transabdominal injection of dyes for…
WHICH OF THE FOLLOWING PATIENTS COULD MOST BENEFIT FROM ADMINISTRATION OF 17 ALPHA-HYDROXYPROGESTERONE CAPROATE
A. A patient with two previous spontaneous preterm births ✓ B. A smoker C. A primigravida D. A person presenting with preterm premature rupture of membranes 17 alpha-hydroxyprogesterone caproate (17P) is a synthetic form of progesterone that has been…
WHICH PRINCIPLE IS MOST IMPORTANT IN THE PROPER CONDUCT OF A VACUUM EXTRACTION DELIVERY
A. Cup size B. Station of presenting part C. Type of cup D. Placement of cup ✓ In the proper conduct of a vacuum extraction delivery, the principle of correct placement of the cup is crucial. The vacuum extraction…
WHEN THE SECOND STAGE OF LABOR EXCEEDS 3 H
A. It should be considered abnormal B. Cesarean or instrumental vaginal delivery should be performed C. It may be normal, depending on the rate of fetal descent ✓ D. Pelvic floor injury is inevitable The duration of the second…
THE LABORS OF MULTIPARAS WHO HAVE HAD ALL PREVIOUS BABIES BY CESAREAN SECTION
A. Are generally prolonged B. Have abnormal contractility patterns C. Are not influenced by maternal age D. Should have their progress judged by the criteria for nulliparas ✓ When considering the labors of multiparas who have had all previous…
THE FIRST-LINE TREATMENT OF ITP IS
A. Administration of corticosteroids ✓ B. Administration of intravenous immunoglobulin (IVIG) C. A splenectomy D. Administration of azathioprine The first-line treatment for Immune Thrombocytopenic Purpura (ITP) is the administration of corticosteroids. Corticosteroids, such as prednisone or dexamethasone, are commonly…
THE MOST ABUNDANT COMPONENT OF SURFACTANT IS
A. SP-A B. PG C. Lecithin (phosphatidylcholine) ✓ D. Sphingomyelin The most abundant component of surfactant is Lecithin (phosphatidylcholine). Surfactant is a complex mixture of lipids and proteins that lines the alveoli in the lungs and plays a crucial…
THE MOST COMMON CAUSE OF SPORADIC PREGNANCY LOSS IN THE FIRST TRIMESTER IS
A. Infection B. Tobacco exposure C. Genetic abnormalities ✓ D. Diabetes E. Thyroid disease The most common cause of sporadic pregnancy loss in the first trimester is Genetic abnormalities. Genetic abnormalities can occur due to errors in the division…
THE MOST COMMON TRISOMY IN SPONTANEOUS ABORTION IS
A. Trisomy 21 B. Trisomy 18 C. Trisomy 13 D. Trisomy 16 ✓ E. Trisomy 1 The most common trisomy in spontaneous abortion is Trisomy 16. Trisomy 16 is the most frequent chromosomal abnormality found in spontaneous abortions, accounting…
THE PLACENTAL EXPRESSION OF WHICH ENZYME IS THOUGHT TO PROTECT THE FETUS FROM MATERNAL CORTISOL
A. Aldosterone synthase B. 11β-Hydroxysteroid dehydrogenase (HSD)-1 C. 11β-HSD-2 ✓ D. 17α-Hydroxylase E. 11α-Hydroxylase The enzyme thought to protect the fetus from maternal cortisol is 11β-Hydroxysteroid dehydrogenase (HSD)-2. This enzyme plays a crucial role in regulating the levels of…
SURFACTANT PROTEIN A (SP-A) IS BELIEVED TO PLAY A ROLE IN
A. The innate immune system of the lung ✓ B. Type 2 cell hyperplasia C. Alveolar development D. Type 2 cell function Surfactant protein A (SP-A) is a crucial component of the innate immune system in the lungs. SP-A…
FIRST-LINE THERAPY FOR APS DURING PREGNANCY INCLUDES
A. High-dose prednisone and low-dose aspirin B. High-dose prednisone and thromboprophylactic doses of heparin C. Thromboprophylactic doses of heparin and low-dose aspirin ✓ D. Intravenous immunoglobulin (IVIG) and low-dose aspirin Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by…
THE ETIOLOGY OF CHRONIC TWIN-TO-TWIN TRANSFUSION SYNDROME
A. Is based on the dizygotic nature of the conceptuses B. Is undoubtedly due to the associated reversed arterial perfusion sequence in the acardiac twin C. Produces hypovolemia and anemia in the recipient and hypervolemia and polycythemia in the donor…
THE BEST METHODOLOGY FOR DETERMINING THE HUMAN RISK OF DEVELOPMENTAL TOXICANTS IS
A. Animal studies B. In vitro studies C. Case reports D. Epidemiology studies ✓ Epidemiology studies are crucial in assessing the impact of environmental exposures on human health, including the effects of developmental toxicants. These studies involve observing and…
A 22-YEAR-OLD Go WITH BIOPSY-CONFIRMED ENDOMETRIOSIS CONTINUES TO HAVE DISABLING DYSMENORRHEA FOR 3 DAYS AT THE TIME OF MENSES DESPITE CYCLIC ORAL CONTRACEPTIVES. WHAT IS THE BEST MANAGEMENT OPTION
A. Endometrial ablation B. Uterine artery embolization C. Danazol/gestrinone D. GnRH agonist (Lupron) E. Continuous OCs ✓ The best management option for a 22-year-old G0 with biopsy-confirmed endometriosis who continues to have disabling dysmenorrhea for 3 days at the time of menses despite cyclic…
A 21-YEAR-OLD PRIMIGRAVID WOMAN PRESENTS WITH FEVER, BACK PAIN, PRETERM LABOR, AND BROWN-STAINED AMNIOTIC FLUID. WHICH OF THE FOLLOWING ORGANISMS SHOULD BE SUSPECTED AS A POTENTIAL CAUSE OF FETAL INFECTION
A. Escherichia coli B. Listeria monocytogenes ✓ C. Group B streptococci D. Trypanosoma cruzi E. Campylobacter fetus When a 21-year-old primigravid woman presents with fever, back pain, preterm labor, and brown-stained amniotic fluid, the potential cause of fetal infection…
THE TREATMENT OF SYPHILIS IN PREGNANCY IN PENICILLIN-ALLERGIC PATIENTS SHOULD CONSIST OF THE ADMINISTRATION OF
A. Penicillin (after desensitization) ✓ B. Erythromycin C. Tetracycline D. Clindamycin Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It can be transmitted from a pregnant woman to her fetus, leading to congenital syphilis, which…
A 24-YEAR-OLD G2P1 PRESENTS AT 36 WEEKS’ GESTATION IN ACTIVE LABOR. HER GBS CULTURE IS NOT AVAILABLE. WHICH OF THE FOLLOWING REPRESENTS THE MOST APPROPRIATE MANAGEMENT IN THIS SETTING
A. Do nothing B. Administer GBS chemoprophylaxis empirically ✓ C. Administer antibiotics only if she develops a fever D. Send a GBS perineal culture and wait for the result to decide whether or not to give antibiotics E. Review her GBS status from her prior…
TREATMENT WITH ISONIAZID (INH) FOR A POSITIVE PURIFIED PROTEIN DERIVATIVE (PPD) CONVERSION DURING PREGNANCY MAY BE ASSOCIATED WITH MATERNAL
A. Renal failure B. Liver toxicity ✓ C. Seizures D. Congestive heart failure Isoniazid (INH) is a medication commonly used to treat tuberculosis and isoniazid preventive therapy (IPT) is recommended for individuals with a positive purified protein derivative (PPD)…
IN PREGNANCY, ACYCLOVIR SHOULD BE USED TO TREAT ALL OF THE FOLLOWING CONDITIONS, EXCEPT FOR
A. Recurrent genital herpes B. Varicella pneumonia C. Herpetic hepatitis D. Influenza ✓ Acyclovir is an antiviral medication commonly used to treat infections caused by herpes viruses, including genital herpes, shingles, and chickenpox. However, it is not typically used…
A 28-YEAR-OLD WOMAN UNDERGOES EXTENSIVE LAPAROSCOPIC SURGERY IN THE LITHOTOMY POSITION. SHE PRESENTS AFTER TWO DAYS WITH UNRESOLVED RIGHT-SIDED FOOT DROP AND PARAESTHESIA OVER THE CALF AND DORSUM OF THE RIGHT FOOT. DAMAGE TO WHICH NERVE IS THE MOST LIKELY CAUSE
A. Common peroneal ✓ B. Femoral C. Ilio-inguinal D. Lateral cutaneous of the thigh E. Obturator The most likely cause of the unresolved right-sided foot drop and paraesthesia over the calf and dorsum of the right foot in this…
MAGNESIUM SULFATE IS COMMONLY ADMINISTERED TO WOMEN WITH PRE-ECLAMPSIA. WHAT IS THE PRIMARY GOAL OF THIS THERAPY
A. To lower the BP B. To prevent preterm labor C. For neuroprotection of the fetus D. To prevent seizures ✓ E. To dilate the cerebral vasculature and prevent headache Pre-eclampsia is a serious condition that can occur during pregnancy, characterized by high blood pressure…
A 46-YEAR-OLD, NON-PREGNANT, MORBIDLY OBESE WOMAN PRESENTS WITH IRREGULAR PERIODS OVER THE PAST 6 MONTHS. WHICH OF THE FOLLOWING REPRESENTS THE MOST APPROPRIATE INITIAL MANAGEMENT IN THIS SETTING
A. Oral contraceptives B. Endometrial ablation C. Office hysteroscopy D. Dilation and curettage (D&C) E. Endometrial biopsy ✓ In this case, the most appropriate initial management for a 46-year-old, non-pregnant, morbidly obese woman presenting with irregular periods over the past 6 months would be…
A PATIENT WHO IS A CHRONIC HEPATITIS B CARRIER DELIVERS VAGINALLY AT 39 WEEKS’ GESTATION. THE BABY SHOULD RECEIVE WHICH OF THE FOLLOWING THERAPIES ON THE FIRST DAY OF LIFE
A. Hepatitis B immune globulin (HBIG) B. Hepatitis B vaccination C. HBIG and hepatitis B vaccination ✓ D. None of the above In the scenario described, where a chronic hepatitis B carrier delivers vaginally at 39 weeks’ gestation, the baby should receive both…
WHICH STRUCTURE PROVIDES THE MAJOR SUPPORT TO THE UTERUS AND CERVIX
A. Round ligaments B. Broad ligaments C. Cardinal ligaments ✓ D. Uterosacral ligaments E. Scarpa fascia The cardinal ligaments provide the major support to the uterus and cervix. These ligaments are located at the base of the broad ligament of the uterus, extending from…
WHICH MEDICINE HAS TO BE DIRECTLY INJECTED INTO THE FETUS
A. Digoxin B. Propranolol C. Flecanide D. Amiodarone ✓ In the case of fetal supraventricular tachycardia (SVT) with hydrops fetalis, amiodarone is the medicine that has to be directly injected into the fetus. Amiodarone is an antiarrhythmic medication that can be…
THE TERM “ZONE OF ALTERED MORPHOLOGY” REFERS TO
A. The zone of amnion, chorion, and decidua in the edge of the placental mass B. The zone of amnion, chorion, and decidua at the midpoint between the placental mass at the site of rupture of membranes C. The zone…
THE MOST COMMON MICROORGANISM ISOLATED BY CULTURE OF AMNIOTIC FLUID IN PRETERM PROM IS
A. Ureaplasma urealyticum ✓ B. Fusobacterium nucleatum C. Mycoplasma hominis D. Escherichia coli E. Group B Streptococcus In cases of preterm premature rupture of membranes (PROM), the most common microorganism isolated by culture of amniotic fluid is Ureaplasma urealyticum. This…
INITIAL TREATMENT FOR MASTITIS INCLUDES A 10 TO 14-DAY COURSE OF A PENICILLINASE-RESISTANT ANTIBIOTIC WITH ADVICE TO THE MOTHER TO
A. Continue nursing with careful attention to thorough breast drainage ✓ B. Pump and discard milk with careful attention to through breast drainage C. Allow the breasts to “rest” removing only enough milk to relief discomfort D. Bind the breasts…
IN INFANTS WITH PERSISTENT PULMONARY HYPERTENSION, WHICH ONE OF THE FOLLOWING MEDICATIONS HAS BEEN DEMONSTRATED BY RANDOMIZED, CONTROLLED TRIALS TO REDUCE THE NEED FOR EXTRACORPOREAL MEMBRANE OXYGENATION
A. Sodium bicarbonate B. Fentanyl (narcotic) C. Pancuronium (paralytic) D. Inhaled nitric oxide ✓ E. Albuterol In infants with persistent pulmonary hypertension, the medication that has been demonstrated by randomized, controlled trials to reduce the need for extracorporeal membrane…
IN A TERM, GROWTH-RETARDED 10-HOUR-OLD NEONATE WITH SOME HYPOTONIA, JITTERINESS, MODERATE TACHYPNEA, AND A BLOOD GLUCOSE OF 10 MG/DL ASSESSED BY A RAPID REAGENT TEST, THE FOLLOWING IS THE MOST APPROPRIATE IMMEDIATE COURSE OF ACTION
A. Send a confirmatory blood glucose sample and start enteral feedings B. Start enteral feedings and send a blood sample for insulin determination C. Send a confirmatory blood glucose sample and start an intravenous glucose infusion ✓ D. Give a…
THE MOST COMMON CAUSE OF POSTPARTUM HEMORRHAGE IS
A. Uterine atony ✓ B. Coagulopathy C. Obstetric trauma D. Retained placenta The most common cause of postpartum hemorrhage is A) Uterine atony. Postpartum hemorrhage is defined as excessive bleeding following childbirth, and uterine atony refers to the inability…
THE FUNDUS COMPRESSION SUTURE USED IN THE MANAGEMENT OF UTERINE BLEEDING WAS DESCRIBED BY
A. O’Leary B. B-Lynch ✓ C. Haultain D. Huntington The B-Lynch suture, also known as the B-Lynch compression suture, is a surgical technique used in the management of postpartum hemorrhage (PPH) or uterine bleeding. It was developed by Dr.…
A PATIENT WITH MARFAN SYNDROME IS CONTEMPLATING PREGNANCY. WHICH OF THE FOLLOWING CLINICAL FINDINGS PLACES HER AT HIGHEST RISK FOR MORTALITY DURING PREGNANCY
A. A grade 2/6 apical diastolic murmur with radiation to the axilla B. An aortic root diameter of 47 mm ✓ C. Marked tricuspid regurgitation D. Unifocal premature ventricular contractions In a patient with Marfan syndrome contemplating pregnancy, an…
IN DIABETIC PATIENTS WHO ARE IN PREMATURE LABOR, THE DRUG OF CHOICE IS
A. A beta-sympathomimetic B. Magnesium sulfate ✓ C. Prostaglandin synthetase inhibitors D. Salbutamol In diabetic patients who are in premature labor, the drug of choice is magnesium sulfate. Magnesium sulfate is commonly used as a tocolytic agent to delay…
THE CONDITION MOST FREQUENTLY MISDIAGNOSED AS APPENDICITIS IS
A. Renal colic B. Round ligament syndrome C. Preterm labor D. Pyelonephritis ✓ E. Cystitis Pyelonephritis is the condition most frequently misdiagnosed as appendicitis. Pyelonephritis is an infection of the kidney and upper urinary tract, usually caused by bacteria…
A PATIENT PRESENTS IN LABOR WITH APPENDICITIS. THE CORRECT MANAGEMENT IS
A. Cesarean section with removal of the appendix B. Vaginal delivery with appendectomy postpartum ✓ C. Appendectomy followed by vaginal delivery D. Appendectomy followed by Cesarean section E. Tocolysis with appendectomy followed by vaginal delivery F. Appendectomy followed by tocolysis…
THE ANTIPHOSPHOLIPID ANTIBODY SYNDROME IS TYPICALLY ASSOCIATED WITH WHICH RENAL DISEASE
A. Thrombotic microangiopathy ✓ B. Minimal change disease C. Focal segmental glomerulosclerosis D. Membranous glomerulopathy Antiphospholipid antibody syndrome (APS) is typically associated with renal disease, particularly thrombotic microangiopathy. Thrombotic microangiopathy is a condition characterized by the formation of blood…
HYPEREMESIS GRAVIDARUM CAN CAUSE A NEUROPATHY BY CAUSING A DEFICIENCY OF WHAT
A. Vitamin B12 B. Vitamin B1 (thiamine) ✓ C. Vitamin C D. Vitamin D E. Vitamin B2 (riboflavin) Hyperemesis gravidarum is a severe form of nausea and vomiting during pregnancy that can lead to various complications, including nutritional deficiencies.…
THE MOST EFFECTIVE TREATMENT FOR SCLERODERMA COMPLICATED WITH RENAL CRISIS DURING PREGNANCY IS
A. Angiotensin-converting enzyme (ACE) inhibitors ✓ B. Corticosteroids C. Nonsteroidal anti-inflammatory drugs (NSAIDs) D. Methotrexate Scleroderma complicated with renal crisis during pregnancy is a serious condition that requires careful management to ensure the health and safety of both the…