THE TREATMENT OF SYPHILIS IN PREGNANCY IN PENICILLIN-ALLERGIC PATIENTS SHOULD CONSIST OF THE ADMINISTRATION OF

• A. Penicillin (after desensitization) ✓
• B. Erythromycin
• C. Tetracycline
• D. Clindamycin

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It can be transmitted from a pregnant woman to her fetus, leading to congenital syphilis, which can result in severe complications for the newborn. Penicillin is the preferred treatment for syphilis in pregnancy due to its effectiveness in treating the infection and preventing adverse outcomes for both the mother and the fetus.

For penicillin-allergic patients who require treatment for syphilis during pregnancy, the recommended approach is desensitization followed by the administration of penicillin. Desensitization involves exposing the patient to gradually increasing doses of the allergen (in this case, penicillin) to induce tolerance and prevent an allergic reaction. Once desensitization is successfully completed, penicillin can be safely administered to treat syphilis in pregnancy.

It is crucial to note that alternative antibiotics such as erythromycin, tetracycline, or clindamycin are not considered first-line treatments for syphilis in pregnancy, especially in penicillin-allergic patients. These antibiotics may not be as effective as penicillin in treating syphilis and preventing complications in both the mother and the fetus.

In summary, for penicillin-allergic patients requiring treatment for syphilis during pregnancy, desensitization followed by the administration of penicillin is the recommended approach to ensure optimal outcomes for both the mother and the baby.