MOLECULAR BASIS OF HEMOGLOBIN DISORDERS
Molecular basis of sickle cell disease Sickle cell disease (SCD) is a genetic disorder caused by a mutation in the hemoglobin gene, specifically in the β-globin chain, resulting in the formation of abnormal hemoglobin called hemoglobin S (HbS). This mutation…
A REVIEW OF PORPHYRINS, HEME AND HEMOGLOBIN
Introduction Porphyrins are organic molecules that play a crucial role in the formation of heme, a vital component in the structure of hemoglobin. Heme is an iron-containing molecule found in red blood cells, which is responsible for binding oxygen and…
WHAT YOU NEED TO KNOW ABOUT HEMOGLOBIN
Introduction Hemoglobin is a protein found in red blood cells that is responsible for transporting oxygen from the lungs to the body’s tissues and carbon dioxide from the tissues back to the lungs to be exhaled. It is a complex…