THE SCIENCE BEHIND SKELETAL MUSCLE DEVELOPMENT
The development of skeletal muscle is a complex and highly regulated process that occurs during embryonic development. It involves the differentiation and fusion of myoblasts, which are the precursor cells of skeletal muscle fibers. This process is tightly controlled by various…
SKELETAL MUSCLE METABOLIC ADAPTATION TO EXERCISE
Skeletal muscle is a highly adaptable tissue that undergoes various metabolic adaptations in response to exercise. These adaptations are crucial for improving muscle performance, endurance, and overall physical fitness. Exercise-induced metabolic changes occur at both the cellular and molecular levels,…
CARDIAC MUSCLE METABOLISM UNDER PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS
Introduction Metabolism in the cardiac muscle plays a crucial role in maintaining the heart’s function under both physiological and pathological conditions. Physiological Conditions: Aerobic Metabolism: Under normal, healthy conditions, the cardiac muscle primarily relies on aerobic metabolism, which means it…
NEUROMUSCULAR JUNCTION AND MECHANISM OF SKELETAL MUSCLE CONTRACTION
Sequence of events at the neuromuscular junction Here’s a step-by-step breakdown: Action Potential: When a nerve impulse (action potential) reaches the end of a motor neuron (presynaptic terminal), it triggers the release of a neurotransmitter called acetylcholine (ACh) from synaptic…
CARDIAC MUSCLE PHYSIOLOGY
Introduction The physiology of cardiac muscle involves several key aspects: Contraction: Cardiac muscle contracts rhythmically to pump blood. It’s involuntary and controlled by electrical impulses from the sinoatrial (SA) node, spreading through the atria and ventricles. Autorhythmicity: Unlike skeletal muscle,…
MOLECULAR MECHANISM OF CONTRACTION IN SKELETAL MUSCLE
Introduction The molecular mechanism of contraction in skeletal muscle involves the sliding filament theory. It occurs when myosin (thick filaments) and actin (thin filaments) interact within the sarcomere, the functional unit of muscle fibers. During muscle contraction, myosin heads bind…
UNDERSTANDING MUSCLE AND NEUROMUSCULAR DISEASES
Introduction Muscle and neuromuscular diseases are a group of conditions that affect the muscles and the nerves that control them. These diseases can be genetic or acquired, and they can affect individuals of all ages. Some common examples of muscle…
UNDERSTANDING THE BASICS OF MUSCLE PHYSIOLOGY
Introduction Muscles are essential for movement and are responsible for generating the force required for various bodily functions. The following is a brief overview of muscle physiology. Muscle Types: There are three types of muscle in the human body: Skeletal…