AUTOMATION OF DNA SEQUENCING
DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule. Automation of DNA sequencing has revolutionized the field of genomics by enabling high-throughput, rapid, and accurate sequencing of DNA. This automation has significantly reduced…
OVERVIEW OF THE DIDEOXY METHOD OF SEQUENCING
The dideoxy method of DNA sequencing, also known as Sanger sequencing, is a widely used technique for determining the nucleotide sequence of DNA. This method was developed by Frederick Sanger and his colleagues in the late 1970s and has since…
OVERVIEW OF MAXAM-GILBERT SEQUENCING
Maxam-Gilbert sequencing, also known as chemical sequencing, is a method for determining the nucleotide sequence of DNA. It was developed by Allan Maxam and Walter Gilbert in 1977 and was one of the first methods for DNA sequencing. This technique…
THE PRINCIPLES OF DNA SEQUENCING
DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule. This technique has revolutionized the field of genetics and has numerous applications in various scientific disciplines, including medicine, agriculture, and evolutionary biology. The principles…
A DEEP DIVE INTO THE SANGER METHOD FOR DNA SEQUENCING
The Sanger method, also known as the chain termination method, is a technique used to determine the sequence of nucleotides in a DNA molecule. This method was developed by Frederick Sanger and his colleagues in the late 1970s and has…
MODERN APPROACHES TO GENOME SEQUENCING AND ANNOTATION
Genome sequencing and annotation have seen significant advancements in recent years, driven by technological innovations and computational tools. Modern approaches to genome sequencing involve high-throughput sequencing technologies, such as next-generation sequencing (NGS) and third-generation sequencing platforms. These technologies have revolutionized…