FIDELITY OF RNA SYNTHESIS
RNA synthesis, also known as transcription, is the process by which a DNA sequence is used as a template to produce a complementary RNA strand. The fidelity of RNA synthesis refers to the accuracy with which the RNA polymerase enzyme…
SYNTHESIS OF cDNA EXPLAINED
cDNA, or complementary DNA, is a crucial molecule in molecular biology and biotechnology. It is synthesized from messenger RNA (mRNA) through the process of reverse transcription. The synthesis of cDNA involves several key steps, including RNA extraction, reverse transcription, and…
SYNTHESIS AND FUNCTION OF CYTOPLASMIC O-GLYCOSYLATION
Cytoplasmic O-glycosylation is a post-translational modification process in which sugar molecules are added to proteins in the cytoplasm of a cell. This type of glycosylation plays crucial roles in various cellular functions, including protein folding, stability, and signaling. The synthesis…
PRODUCTION OF RNA AND PROTEIN SYNTHESIS
Production of RNA: RNA is produced through a process called transcription. The first step in this process is the initiation, where RNA polymerase binds to a specific region of DNA called the promoter. Then, the enzyme unwinds the DNA double…
MECHANISMS OF ACTION OF PROTEIN SYNTHESIS INHIBITORS UNVEILED
Introduction Protein synthesis inhibitors are antibiotics that prevent bacteria from producing essential proteins needed for growth and survival. These antibiotics work by binding to the 30S ribosomal subunit, which is responsible for protein synthesis. The most common mechanism of action…
WHAT YOU NEED TO KNOW ABOUT CHOLESTEROL SYNTHESIS AND DEGRADATION
Liver’s Cholesterol Pool: Input & Output Routes The liver plays a central role in maintaining cholesterol homeostasis in the body. It regulates the cholesterol pool through various sources of input and output routes. Let’s delve into the details: Sources of…
A CLOSER LOOK AT PYRIMIDINE SYNTHESIS
Pyrimidine Synthesis Steps Pyrimidine synthesis is a complex biochemical process that occurs in the body to produce pyrimidine nucleotides, which are essential components of DNA, RNA, and various coenzymes. The synthesis of pyrimidines involves several enzymatic steps and regulatory mechanisms.…
GLOBIN GENES AND MOLECULAR BIOLOGY OF GLOBIN SYNTHESIS
Globin Gene Organization The organization of globin genes, including the beta and alpha gene families, is crucial for the synthesis of hemoglobin proteins, which are responsible for transporting oxygen in red blood cells. Here’s an overview of the organization of…
A BEGINNER’S GUIDE TO UREA SYNTHESIS
Introduction Urea is a compound that is produced in the liver from excess amino acids and other nitrogenous wastes. The synthesis of urea from ammonia and carbon dioxide is called the urea cycle or the Krebs-Henseleit cycle. The urea cycle…