DESCRIBE THE LIFE CYCLE OF ROUNDWORM, SPECIFICALLY ASCARIS LUMBRICOIDES

The life cycle of roundworms, specifically Ascaris lumbricoides, is an essential aspect of understanding their biology, ecology, and the potential health risks they pose to humans. Ascaris lumbricoides, commonly known as the pork worm or human roundworm, is a parasitic roundworm that infests the intestines of humans and other mammals, causing a condition known as ascariasis.

The adult female Ascaris lumbricoides can produce up to 200,000 eggs per day, which are then excreted in the host’s feces. These eggs are microscopic in size, measuring approximately 60-80 μm in length and 50-60 μm in width. They are embryonated and can survive for long periods in the environment, depending on temperature and humidity conditions.

The life cycle of the roundworm Ascaris lumbricoides involves several stages and occurs within the human body.

• Ingestion: The life cycle begins when a person ingests the eggs of Ascaris lumbricoides. These eggs are present in contaminated food or water, particularly in areas with poor sanitation practices. Once inside the human body, the eggs hatch in the small intestine.
• Larval migration: After hatching, the larvae penetrate the intestinal wall and enter the bloodstream. From there, they travel to the liver and then to the lungs through the circulatory system. In the lungs, the larvae migrate through the lung tissue and reach the airways.
• Coughing and swallowing: The larvae are then coughed up from the airways and subsequently swallowed. This brings them back into the digestive system, specifically into the stomach.
• Maturation: Once in the stomach, the larvae develop into adult worms. They grow rapidly and can reach lengths of up to 30 centimeters. The adult worms then move from the stomach to the small intestine, where they attach themselves to the intestinal wall using their mouthparts and feed on the host’s blood and tissue.
• Reproduction: The adult male and female worms mate in the small intestine. The female produces large quantities of eggs, which are released into the intestinal lumen and subsequently passed out of the body through feces and the life cycle of Ascaris lumbricoides continues as described in the first stage.
• Environmental development: The eggs need to undergo maturation outside of the human body before they become infectious again. In favorable conditions (moisture and warmth), it takes about two to three weeks for the eggs to develop into an infective stage.
• Transmission: If proper sanitation measures are not in place, contaminated soil can harbor infective eggs for a long period. When a person comes into contact with this soil, either through direct contact or ingestion of contaminated food or water, the cycle restarts as the eggs are ingested.

This life cycle allows Ascaris lumbricoides to persist in populations with poor sanitation practices, leading to a high prevalence of ascariasis in some regions.