THE MOST COMMON TRISOMY IN SPONTANEOUS ABORTION IS

• A. Trisomy 21
• B. Trisomy 18
• C. Trisomy 13
• D. Trisomy 16 ✓
• E. Trisomy 1

The most common trisomy in spontaneous abortion is Trisomy 16. Trisomy 16 is the most frequent chromosomal abnormality found in spontaneous abortions, accounting for approximately 20-25% of all miscarriages. This condition occurs when there is an extra copy of chromosome 16, leading to developmental abnormalities that are not compatible with life.

Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome), and Trisomy 13 (Patau syndrome) are more commonly associated with live births rather than spontaneous abortions. Trisomy 1 is not a known chromosomal abnormality in humans.

In other words, in spontaneous abortions, trisomies are a common cause of pregnancy loss. Trisomy refers to a genetic condition where there is an extra copy of a chromosome. The most common trisomy found in spontaneous abortions is Trisomy 16.

Explanation:

1. Trisomy 21 (Down Syndrome): Trisomy 21 is the most common trisomy that survives to term and is associated with Down syndrome. However, it is not the most common trisomy found in spontaneous abortions.
2. Trisomy 18 (Edwards Syndrome): Trisomy 18, also known as Edwards syndrome, involves an extra chromosome 18. While it is a common chromosomal abnormality, it is not the most prevalent in spontaneous abortions.
3. Trisomy 13 (Patau Syndrome): Trisomy 13, or Patau syndrome, results from an extra chromosome 13. It leads to severe intellectual disability and physical abnormalities but is not the most frequent trisomy in spontaneous abortions.
4. Trisomy 16: Trisomy 16 is the most common chromosomal abnormality found in early miscarriages or spontaneous abortions. It often leads to pregnancy loss before the fetus can develop further.
5. Trisomy 1: Trisomies involving chromosome 1 are rare and not typically associated with spontaneous abortion.